The 12.1 inch Vertical Screen for the Ford F-150 2015- 2017 is compatible if your truck has a dashboard that resembles the pictures below.

Image result for ford f-150 interior 2016

If the dashboard of your truck resembles the picture below, then the unit is not compatible. 

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*Please note that this unit has three slots of buttons on top. 

For the auto A/C or digital climate control it is the first picture on the top that has auto marking on the bottom left knob. 

For the manual A/C or analog climate control it is the second picture from the top which has max A/C marking on the bottom right knob.